Gas-Chromatographic Determination of an Antifibrinolytic Drug, E-Aminocaproic Acid
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چکیده
We describe a modified method for assay of t-aminocaproic acid. Serum or cerebrospinal fluid is deproteinized, followed by cation-exchange column-chromatography, and N-trifluoroacetyl-n-butyl derivativesof amino acids are formed and separatedby gas chromatography.Tranexamic acid,a nonproteinamino acid,was used as an internal standard.The assay issensitiveand precise,and results correlate adequately with those obtained with an automated amino acid analyzer (ion-exchange chromatography).
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تاریخ انتشار 2004